2nd BDS Year SYLLABUS
 
   SYLLABUS
 
  General Pathology and Microbiology
General and Dental Pharmacology and Therapeutics
  Dental Materials
  Pre Clinical Conservative Dentistry
  Pre Clinical Prosthodontics, Crown and Bridge
   

General Pathology and Microbiology

   

Paper No. –I : General Pathology and Microbiology

Teaching Scheme

Examination Scheme

Total Marks

Hours Per year

Lectures Practicals
120 105

225 Hrs

Theory Marks

Final Viva Voce Internal
70 20 10

100

Practical Marks
Final Internal
90 10

100

200
     

GENERAL PATHOLOGY

     
  AIM:
   

At the end of the course the student should be competent to:

   

Apply the scientific study of disease processes, which result in morphological and functional alterations in cells, tissues and organs to the study of pathology and the practice of dentistry.

  OBJECTIVES :
    Enabling the student
  1.

To demonstrate and apply basic facts, concepts and theories in the field of Pathology.

  2.

To recognize and analyze pathological changes at macroscopically and microscopical levels and explain their observations in terms of disease processes.

  3.

To Integrate knowledge from the basic sciences, clinical medicine and dentistry in the study of Pathology.

  4.

To demonstrate understanding of the capabilities and limitations of morphological Pathology in its contribution to medicine, dentistry and biological research.

  5.

To demonstrate ability to consult resource materials outside lectures, laboratory and tutorial classes.

     
    COURSE CONTENT
  A. General Pathology –
  1. Introduction to Pathology
    Terminologies
    The cell in health
    The normal cell structure
    The cellular functions
  2. Etiology and Pathogenesis of Disease
    Cell Injury
    Types – Congenital
    Acquired
    Mainly Acquired causes of disease
    (Hypoxic injury, chemical injury, physical injury, immunological injury)
  3. Degenerations
    Amyloidosis
    Fatty change
    Cloudy swelling
    Hyaline change, mucoid degeneration
  4. Cell death & Necrosis
    Apoptasis
    Def, causes, features and types of necrosis
    Gangrene - Dry, wet, gas
    Pathological Calcifications
    (Dystrophic and metastatic)
  5. Inflammation
    Definition, causes types, and features
    Acute inflammation
   
a. The vascular response
b. The cellular response
c. Chemical mediators
d. The inflammatory cells
e. Fate
    Chronic inflammation
    Granulomations inflammation
  6. Healing
    Regeneration
    Repair
   
a. Mechanisms
b. Healing by primary intention
c. Healing by secondary intention
d. Fracture healing
e. Factors influencing healing process
f. Complications
  7. Tuberculosis
    Epidemiology
    Pathogenesis ( Formation of tubercle)
    Pathological features of Primary and secondary TB
    Complications and Fate
  8. Syphilis
    Epidemiology
    Types and stages of syphilis
    Pathological features
    Diagnostic criterias
    Oral lesions
  9. Typhoid
    Epidemiology
    Pathogenesis (Formation of tuberecle
    Pathological features
    Diagnostic criterias
  10. Thrombosis
    Definition, Pathophysiology
    Formation, complications & Fate of a thrombus
  11. Embolism
    Definition
    Types
    Effects
  12. Ischaemia and Infraction
    Definition, etiology, types
    Infraction of various organs
  13. Derangements of body fluids
    Oedema – pathogenesis
    Different types
  14. Disorders of circulation
    Hyperaemia
    Shock
  15. Nutritional Disorders
    Common Vitamin Deficiencies
  16. Immunological mechanisms in disease
    Humoral & cellular immunity
    Hypersensitivity & autommunity
  17. AIDS
  18. Hypertension
    Definition, classification
    Pathophysiology
    Effects in various organs
  19. Diabetes Mellitus
    Def, Classification, Pathogenesis, Pathology in different organs
  20. Adaptive disorders of growth
    Atrophy & Hypertrophy, Hyperplasia, Metaplasia and Dysplasia
  21. General Aspects of neoplesia
   
a. Definition, terminology, classification
b. Differences between benign and malignant neoplasms
c. The neoplastic cell
d. Metastasis
e. Etiology and pathogenesis of neoplasia, Carcinogenesis
f. Tumour biology
g. Oncogenes and anti-oncogenes
h. Diagnosis
i. Precancerous lesions
j.

Common specific tumours, Sq papilloma & Ca, Basal cell Ca, Adenoma & Adenoca, Fibroma & Fibrosarcoma, Lipoma and liposarcoma

  B. Systemic Pathology
  22 Anaemias
    Iron Deficiency anaemia, Megaloblastic anaemia
  23. Leukaemias
    Acute and chronic leukaemias, Diagnosis and clinical features
  24. Diseases of Lymph nodes
    Hodgkin’s disease, Non Hodgkins lymphoma, Metastatic carcinoma
  25. Diseases of oral cavity
    Lichen planus, Stomatitis, Leukoplakia, Sq cell Ca, Dental caries, Dentigerious cyst, Ameloblastoma
  26. Diseases of salivary glands
    Normal structure, Sialadenitis, Tumours
  27. Common diseases of Bones
   

Osteomyelitis, Metabolic bone diseases, Bone Tumours, Osteosarcoma, Osteocalstoma, Giant cell Tumour, Ewing’s sarcoma, Fibrous dysplasia, Aneurysmal bone cyst

  28. Diseases of Cardiovascular system
    Cardiac failuare
    Congenital heart disease
    ASD, VSD,PDA Fallot’s Tetrology
    Infective Endocarditis
    Atherosclerosis
    Ischaemic heart Disease
  29. Haemorrhagic Disorders
    Coagulation cascade
    Coagulation disorders
    Platelet funtion
    Platelet disorders
     
    PRACTICALS
  1. Urine
    Abnormal constitutients
    Sugar, albumin, ketone bodies
  2. Urine – Abnormal consittuents
    Blood, bile salts, bile pigments
  3. Haemoglobin (Hb) estimation
  4. Total WBC count
  5. Differential WBC Count
  6. Packed cell volume(PCV,) rythrocyte sedimentation Rate (ESR)
  7. Bleeding Time & clotting Time
  8. Histopathology
    Tissue Processing
    Staining
  9. Histopathology slides
    Acute appendicitis, Granulation tissue, fatty liver
  10. Histopathology slides
    CVC lung, CVC liver, Kidney amyloidosis
  11. Histopathology slides
    Tuberculosis, Actionomycosis, Rhinosporidiosis
  12. Histopathology slides
    Papilloma, Basal cell Ca, Sq cell Ca
  13. Histopathology slides
    Osteosarcoma, osteoclastoma, fibrosarcoma
  14. Histopathology slides
    Malignant melanoma, Ameloblastoma, Adenoma
  15. Histopathology slides
    Mixed parotid tumour, metastatic carcinoma in lymph node
     
    LIST OF TEXTBOOKS
  1. Robbins – Pathologic Basis of Disease Cotran, Kumar, Robbins
  2. Anderson’s Pathology Vol 1 & 2 Editors – Ivan Damjanov & James Linder
  3. Wintrobe’s clinical Haematolog Lee, Bithell, Foerster, Athens, Lukens
     
    MICROBIOLOGY
     
    AIM:
   

To introduce the students to the exciting world of microbes. To make the students aware of various branches of microbiology, importance, significance and contribution of each branch to mankind and other fields of medicine. The objectives of teaching microbiology can be achieved by various teaching techniques such as :

   
a) Lectures b) Lecture Demonstrations
c) Practical exercises d) Audio visual aids
e) Small group discussions with regular feed back from the students.
     
    OBJECTIVES
  A. Knowledge and Understanding
    At the end of the Microbiology course the student is expected to :
  1.

Understand the basics of various branches of microbiology and able to apply the knowledge relevantly.

  2.

Apply the knowledge gained in related medical subjects like General Medicine and General Surgery and Dental subjects like Oral Pathology, Community Dentistry, Periodontics, Oral Surgery, Pedodontics, Conservative Dentistry and Oral medicine in higher classes.

  3.

Understand and practice various methods of Sterilisation and disinfection in dental clinics.

  4.

Have a sound understanding of various infectious diseases and lesions in the oral cavity.

     
  B. SKILLS
  1.

Student should have acquired the skill to diagnose, differentiate various oral lesions.

  2.

Should be able to select, collect and transport clinical specimens to the laboratory.

  3. Should be able to carry out proper aseptic procedures in the dental clinic.
     
    A brief syllabus of Microbiology is given as follows:
     
  A. GENERAL MICROBIOLOGY:
  1. History, Introduction, Scope, Aims and Objectives.
  2. Morphology and Physiology of bacteria.
  3. Detail account of Sterlisation and Disinfection.
  4. Brief account of Culture media and Culture techniques
  5.

Basic knowledge of selection, collection, transport, processing of clinical Specimens and identification of bacteria.

  6. Bacterial Genetics and Drug Resistance in bacteria.
     
  B. IMMUNOLOGY:
  1. Infection - Definition, Classification, Source, Mode of transmission and types of Infectious disease.
  2. Immunity
  3. Structure and functions of Immune system
  4. The Complement System
  5. Antigen
  6.

Immunoglobulins - Antibodies - General structure and the role played in defense mechanism of the body.

  7. Immune response
  8. Antigen - Antibody reactions - with reference to clinical utility.
  9.

Immuno deficiency disorders - a brief knowledge of various types of immuno deficiency disorders - A sound knowledge of immuno deficiency disorders relevant to dentistry.

  10. Hypersensitivity reactions
  11.

ic knowledge of various types - sound knowledge of autoimmune disorders of oral cavity and related structures.

  12. Immunology of Transplantation and Malignancy
  13. Immunehaematology
     
  C. SYSTEMATIC BACTERIOLOGY:
  1.

Pyogenic cocci - Staphylococcus, Streptococcus, Pneumococcus, Gonococcus, Meningococcus – brief account of each coccus - detailed account of mode of spread, laboratory diagnosis, Chemo therapy and prevention - Detailed account of Cariogenic Streptococci.

  2.

Corynebacterium diphtheriae - mode of spread, important clinical feature, Laboratory diagnosis, Chemotherapy and Active immunisation.

  3. Mycobacteria - Tuberculosis and Leprosy
  4. Clostridium - Gas gangrene, food poisoning and tetanus.
  5.

Non-sporing Anaerobes - in brief about classification and morphology, in detail about dental pathogens - mechanism of disease production and prevention.

  6.

Spirochaetes - Treponema pallidum - detailed account of Oral Lesions of syphilis, Borrelia vincentii.

  7. Actinomycetes.
     
  D. VIROLOGY:
  1. Introduction
  2.

General properties, cultivation, host - virus interaction with special reference to Interferon.

  3.

Brief account of Laboratory diagnosis, Chemotherapy and immuno prophylaxis in general.

  4. A few viruses of relevance to dentistry.
    Herpes Virus
    Hepatitis B Virus - brief about other types
    Human Immunodeficiency Virus (HIV)
    Mumps Virus
    Brief - Measles and Rubella Virus
  5. Bacteriophage - structure and Significance
     
  E. MYCOLOGY
  1. Brief Introduction
  2. Candidosis - in detail
  3. Briefly on oral lesions of systemic mycoses.
     
  F. PARASITOLOGY:
  1. Brief introduction - protozoans and helminths
  2.

Brief knowledge about the mode of transmission and prevention of commonly seen parasitic infection in the region.

     
    RECOMMENDED BOOKS FOR REGULAR READING:
     
  1. Text book of Microbiology – R.Ananthanarayan & C.K.Jayaram Paniker.
  2. Medical Microbiology – David Greenwood et al.
     
    BOOKS FOR FURTHER READING/REFERENCE.
     
  1. Microbiology – Prescott, etal.
  2. Microbiology – Bernard D. Davis , et al.
  3. Clinical & Pathogenic Microbiology – Barbara J Howard, etal.
  4. Mechanisms of Microbial diseases – Moselio Schaechter, etal.
  5. Immunology an Introduction – Tizard
  6. Immunology 3rd edition – Evan Roitt , etal.
 
 
 
 
 
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